There are two mathematical models of elastic walls of healthy and atherosclerotic blood vessels developed and studied. The models are included in a numerical model of global blood circulation via recovery of the vessel wall state equation. The joint model allows us to study the impact of arteries atherosclerotic disease of a set of arteries on regional haemodynamics.
We present the fiber-spring elastic model of the arterial wall with atherosclerotic plaque composed of a lipid pool and a fibrous cap. This model allows us to reproduce pressure to cross-sectional area relationship along the diseased vessel which is used in the network model of global blood circulation. Atherosclerosis attacks a region of systemic arterial network. Our approach allows us to examine the impact of the diseased region onto global haemodynamics....
This paper proposes a quantitative model of the reaction-diffusion type to examine the distribution of interferon- (IFN) in a lymph node (LN). The numerical treatment of the model is based on using an original unstructured mesh generation software Ani3D and nonlinear finite volume method for diffusion equations. The study results in suggestion that due to the variations in hydraulic conductivity of various zones of the secondary lymphoid organs the...
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