Systems of differential equations with state-dependent delay are considered. The delay dynamically depends on the state, i.e. is governed by an additional differential equation. By applying the time transformations we arrive to constant delay systems and compare the asymptotic properties of the original and transformed systems.
A virus dynamics model with two state-dependent delays and logistic growth term is investigated. A general class of nonlinear incidence rates is considered. The model describes the in-host interplay between viral infection and CTL (cytotoxic T lymphocytes) and antibody immune responses. The wellposedness of the model proposed and Lyapunov stability properties of interior infection equilibria which describe the cases of a chronic disease are studied. We choose a space of merely continuous initial...
Inertial manifold with delay (IMD) for dissipative systems of second order in time is constructed. This result is applied to the study of different asymptotic properties of solutions. Using IMD, we construct approximate inertial manifolds containing all the stationary solutions and give a new characterization of the K-invariant manifold.
We propose a virus dynamics model with reaction-diffusion and logistic growth terms, intracellular state-dependent delay and a general non-linear infection rate functional response. Classical solutions with Lipschitz in-time initial functions are investigated. This type of solutions is adequate to the discontinuous change of parameters due to, for example, drug administration. The Lyapunov functions approach is used to analyse stability of interior infection equilibria which describe the cases of...
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