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An Iterative Bézier Method for Fitting Beta-sheet Component of a Cryo-EM Density Map

Michael PoteatJing He — 2017

Molecular Based Mathematical Biology

Cryo-electron microscopy (Cryo-EM) is a powerful technique to produce 3-dimensional density maps for large molecular complexes. Although many atomic structures have been solved from cryo-EM density maps, it is challenging to derive atomic structures when the resolution of density maps is not sufficiently high. Geometrical shape representation of secondary structural components in a medium-resolution density map enhances modeling of atomic structures.We compare two methods in producing surface representation...

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