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Let $k\ge 5$ be an odd integer and $\eta$ be any given real number. We prove that if ${\lambda }_1$, ${\lambda }_2$, ${\lambda }_3$, ${\lambda }_4$, $\mu$ are nonzero real numbers, not all of the same sign, and ${\lambda }_1/{\lambda }_2$ is irrational, then for any real number $\sigma$ with $0<\sigma <1/\left(8\vartheta \right(k\left)\right)$, the inequality $$|{\lambda }_1{p}_1^2+{\lambda }_2{p}_2^2+{\lambda }_3{p}_3^2+{\lambda }_4{p}_4^2+\mu p_5^k+\eta |<{\left(\underset{1\le j\le 5}{max}{p}_j\right)}^{-\sigma }$$ has infinitely many solutions in prime variables $p_1,p_2,\cdots ,p_5$, where $\vartheta \left(k\right)=3\times 2^{(k-5)/2}$ for $k=5,7,9$ and $\vartheta \left(k\right)=[(k^2+2k+5)/8]$ for odd integer $k$ with $k\ge 11$. This improves a recent result in W. Ge, T. Wang (2018).