Displaying similar documents to “Modeling the Dynamics of the Cardiovascular-respiratory System (CVRS) in Humans, a Survey”

Identification of parametric models with a priori knowledge of process properties

Krzysztof B. Janiszowski, Paweł Wnuk (2016)

International Journal of Applied Mathematics and Computer Science

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An approach to estimation of a parametric discrete-time model of a process in the case of some a priori knowledge of the investigated process properties is presented. The knowledge of plant properties is introduced in the form of linear bounds, which can be determined for the coefficient vector of the parametric model studied. The approach yields special biased estimation of model coefficients that preserves demanded properties. A formula for estimation of the model coefficients is derived...

On parameter estimation in an in vitro compartmental model for drug-induced enzyme production in pharmacotherapy

Jurjen Duintjer Tebbens, Ctirad Matonoha, Andreas Matthios, Štěpán Papáček (2019)

Applications of Mathematics

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A pharmacodynamic model introduced earlier in the literature for in silico prediction of rifampicin-induced CYP3A4 enzyme production is described and some aspects of the involved curve-fitting based parameter estimation are discussed. Validation with our own laboratory data shows that the quality of the fit is particularly sensitive with respect to an unknown parameter representing the concentration of the nuclear receptor PXR (pregnane X receptor). A detailed analysis of the influence...

Set-membership identifiability of nonlinear models and related parameter estimation properties

Carine Jauberthie, Louise Travé-Massuyès, Nathalie Verdière (2016)

International Journal of Applied Mathematics and Computer Science

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Identifiability guarantees that the mathematical model of a dynamic system is well defined in the sense that it maps unambiguously its parameters to the output trajectories. This paper casts identifiability in a set-membership (SM) framework and relates recently introduced properties, namely, SM-identifiability, μ-SM-identifiability, and ε-SM-identifiability, to the properties of parameter estimation problems. Soundness and ε-consistency are proposed to characterize these problems and...

Two methods for optical flow estimation

Frolkovič, Peter, Kleinová, Viera

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In this paper we describe two methods for optical flow estimation between two images. Both methods are based on the backward tracking of characteristics for advection equation and the difference is on the choice of advection vector field. We present numerical experiments on 2D data of cell nucleus.

Set membership estimation of parameters and variables in dynamic networks by recursive algorithms with a moving measurement window

Kazimierz Duzinkiewicz (2006)

International Journal of Applied Mathematics and Computer Science

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The paper considers a set membership joint estimation of variables and parameters in complex dynamic networks based on parametric uncertain models and limited hard measurements. A recursive estimation algorithm with a moving measurement window is derived that is suitable for on-line network monitoring. The window allows stabilising the classic recursive estimation algorithm and significantly improves estimate tightness. The estimator is validated on a case study regarding a water distribution...

Modeling and simulation of a blood pump for the development of a left ventricular assist system controller

Yih-Choung Yu, J. Robert Boston, Marwan A. Simaan, Phil J. Miller, James F. Antaki (1999)

Kybernetika

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A mathematical model describing the pressure-volume relationship of the Novacor left ventricular assist system (LVAS) was developed. The model consisted of lumped resistance, capacitance, and inductance elements with one time-varying capacitor to simulate the cyclical pressure generation of the system. The ejection and filling portions of the pump cycle were modeled with two separate functions. The corresponding model parameters were estimated by least squares fit to experimental data...

Monitoring of chlorine concentration in drinking water distribution systems using an interval estimator

Rafał Łangowski, Mietek Brdys (2007)

International Journal of Applied Mathematics and Computer Science

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This paper describes the design of an interval observer for the estimation of unmeasured quality state variables in drinking water distribution systems. The estimator utilizes a set bounded model of uncertainty to produce robust interval bounds on the estimated state variables of the water quality. The bounds are generated by solving two differential equations. Hence the numerical efficiency is sufficient for on-line monitoring of the water quality. The observer is applied to an exemplary...

Mathematical Model of Blood Flow in an Anatomically Detailed Arterial Network of the Arm

Sansuke M. Watanabe, Pablo J. Blanco, Raúl A. Feijóo (2013)

ESAIM: Mathematical Modelling and Numerical Analysis - Modélisation Mathématique et Analyse Numérique

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A distributed-parameter (one-dimensional) anatomically detailed model for the arterial network of the arm is developed in order to carry out hemodynamics simulations. This work focuses on the specific aspects related to the model set-up. In this regard, stringent anatomical and physiological considerations have been pursued in order to construct the arterial topology and to provide a systematic estimation of the involved parameters. The model comprises 108 arterial segments, with 64...

A Galerkin strategy with Proper Orthogonal Decomposition for parameter-dependent problems – Analysis, assessments and applications to parameter estimation

D. Chapelle, A. Gariah, P. Moireau, J. Sainte-Marie (2013)

ESAIM: Mathematical Modelling and Numerical Analysis - Modélisation Mathématique et Analyse Numérique

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We address the issue of parameter variations in POD approximations of time-dependent problems, without any specific restriction on the form of parameter dependence. Considering a parabolic model problem, we propose a POD construction strategy allowing us to obtain some error estimates controlled by the POD remainder – in the construction procedure – and some parameter-wise interpolation errors for the model solutions. We provide a thorough numerical assessment of this strategy with the...