Displaying similar documents to “Intensified Doxorubicin-Based Regimen Efficacy in Residual Non-Hodgkin's Lymphoma Disease: Towards a Computationally Supported Treatment Improvement”

Tumour angiogenesis model with variable vessels' effectiveness

Jan Poleszczuk, Iwona Skrzypczak (2011)

Applicationes Mathematicae

Similarity:

We propose a model of vascular tumour growth, which generalises the well recognised model formulated by Hahnfeldt et al. in 1999. Our model is based on the same idea that the carrying capacity for any solid tumour depends on its vessel density but it also incorporates vasculature quality which may be lost during angiogenesis as recognised by Jain in 2005. In the model we assume that the loss of vessel quality affects the diffusion coefficient inside the tumour. We analyse basic mathematical...

The Effect of Bacteria on Epidermal Wound Healing

E. Agyingi, S. Maggelakis, D. Ross (2010)

Mathematical Modelling of Natural Phenomena

Similarity:

Epidermal wound healing is a complex process that repairs injured tissue. The complexity of this process increases when bacteria are present in a wound; the bacteria interaction determines whether infection sets in. Because of underlying physiological problems infected wounds do not follow the normal healing pattern. In this paper we present a mathematical model of the healing of both infected and uninfected wounds. At the core of our...

The onset of necrosis in a 3D cellular automaton model of EMT6 multi-cellular spheroids

Simon D. Angus, Monika J. Piotrowska (2010)

Applicationes Mathematicae

Similarity:

A 3-dimensional (3D) extension to a previously reported scaled 2-dimensional Cellular Automaton (CA) model of avascular multi-cellular spheroid growth is presented and analysed for the EMT6/Ro cell line. The model outputs are found to compare favourably with reported experimentally obtained data for in vitro spheroids of the same cell line. Necrosis (unprogrammed central cell death) is observed to be delayed when compared with the experimental data. Furthermore, it is found that necrosis...

Mathematical model of tumour cord growth along the source of nutrient

S. Astanin, A. Tosin (2010)

Mathematical Modelling of Natural Phenomena

Similarity:

A mathematical model of the tumour growth along a blood vessel is proposed. The model employs the mixture theory approach to describe a tissue which consists of cells, extracellular matrix and liquid. The growing tumour tissue is supposed to be surrounded by the host tissue. Tumours where complete oxydation of glucose prevails are considered. Special attention is paid to consistent description of oxygen consumption and growth processes based on the energy balance. A finite difference...