Displaying similar documents to “HIV-1 integrase-DNA interactions investigated by molecular modelling.”

Improving Cancer Therapy by Doxorubicin and Granulocyte Colony-Stimulating Factor: Insights from a Computerized Model of Human Granulopoiesis

V. Vainstein, Y. Ginosar, M. Shoham, A. Ianovski, A. Rabinovich, Y. Kogan, V. Selitser, Z. Agur (2010)

Mathematical Modelling of Natural Phenomena

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Neutropenia is a significant dose-limiting toxicity of cancer chemotherapy, especially in dose-intensified regimens. It is widely treated by injections of Granulocyte Colony-Stimulating Factor (G-CSF). However, optimal schedules of G-CSF administration are still not determined. In order to aid in identifying more efficacious and less neutropenic treatment protocols, we studied a detailed physiologically-based computer model of granulopoiesis, as affected by different treatment schedules...

Thermodynamics of DNA microarrays

Enrico Carlon (2008)

Banach Center Publications

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DNA microarrays have been widely used in molecular biology laboratories. The main current application of these devices is the determination of the gene expression level for thousands of genes simultaneously. Here we review a recently introduced physical model for hybridization (i.e. the binding of complementary DNA strands) in Affymetrix arrays and compare it to experimental results. The experimental data follow rather well the microscopic model and the approach offers several advantages...

Multiagent opinion dynamics influenced by individual susceptibility and anchoring effect

Zihan Chen, Yu Xing, Huashu Qin (2019)

Kybernetika

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This paper studies a new model of social opinion dynamics in multiagent system by counting in two important factors, individual susceptibility and anchoring effect. Different from many existing models only focusing on one factor, this model can exhibit not only agreement phenomena, but also disagreement phenomena such as clustering and fluctuation, during opinion evolution. Then we provide several conditions to show how individual susceptibility and anchoring effect work on steady-state...

Modeling Pulsatility in the Human Cardiovascular System

de los Reyes V, Aurelio, Kappel, Franz (2010)

Mathematica Balkanica New Series

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AMS Subj. Classification: 92C30 In this study we investigated, modified and combined two existing mathematical cardiovascular models, a non-pulsatile global model and a simplified pulsatile left heart model. The first goal of the study was to integrate these models. The main objective is to have a global lumped parameter pulsatile model that predicts the pressures in the systemic and pulmonary circulation, and specifically the pulsatile pressures in the the finger arteries where...