Displaying similar documents to “Fluid-retention side-effects of the chemotherapy-supportive treatment interleukin-11: mathematical modelling of putative underlying mechanisms.”

Modeling Pulsatility in the Human Cardiovascular System

de los Reyes V, Aurelio, Kappel, Franz (2010)

Mathematica Balkanica New Series

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AMS Subj. Classification: 92C30 In this study we investigated, modified and combined two existing mathematical cardiovascular models, a non-pulsatile global model and a simplified pulsatile left heart model. The first goal of the study was to integrate these models. The main objective is to have a global lumped parameter pulsatile model that predicts the pressures in the systemic and pulmonary circulation, and specifically the pulsatile pressures in the the finger arteries where...

Mathematical Model of Fibrin Polymerization

A.I. Lobanov, A.V. Nikolaev, T.K. Starozhilova (2011)

Mathematical Modelling of Natural Phenomena

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Blood clotting system (BCS) modelling is an important issue with a plenty of applications in medicine and biophysics. The BCS main function is to form a localized clot at the site of injury preventing blood loss. Mutual influence of fibrin clot consisting mainly of fibrin polymer gel and blood flow is an important factor for BCS to function properly. The process of fibrin polymer mesh formation has not adequately been described by current mathematical models. That is why it is not possible...

Multiagent opinion dynamics influenced by individual susceptibility and anchoring effect

Zihan Chen, Yu Xing, Huashu Qin (2019)

Kybernetika

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This paper studies a new model of social opinion dynamics in multiagent system by counting in two important factors, individual susceptibility and anchoring effect. Different from many existing models only focusing on one factor, this model can exhibit not only agreement phenomena, but also disagreement phenomena such as clustering and fluctuation, during opinion evolution. Then we provide several conditions to show how individual susceptibility and anchoring effect work on steady-state...

Improving Cancer Therapy by Doxorubicin and Granulocyte Colony-Stimulating Factor: Insights from a Computerized Model of Human Granulopoiesis

V. Vainstein, Y. Ginosar, M. Shoham, A. Ianovski, A. Rabinovich, Y. Kogan, V. Selitser, Z. Agur (2010)

Mathematical Modelling of Natural Phenomena

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Neutropenia is a significant dose-limiting toxicity of cancer chemotherapy, especially in dose-intensified regimens. It is widely treated by injections of Granulocyte Colony-Stimulating Factor (G-CSF). However, optimal schedules of G-CSF administration are still not determined. In order to aid in identifying more efficacious and less neutropenic treatment protocols, we studied a detailed physiologically-based computer model of granulopoiesis, as affected by different treatment schedules...