Statistical models to study subtoxic concentrations for some standard mutagens in three colon cancer cell lines.

Xavier Bardina; Laura Fernández; Elisabet Piñeiro; Jordi Surrallés; Antonia Velázquez

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Displaying similar documents to “Statistical models to study subtoxic concentrations for some standard mutagens in three colon cancer cell lines.”

An application of nonprarametric Cox regression model in reliability analysis: a case study

Petr Volf (2004)

Kybernetika

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The contribution deals with an application of the nonparametric version of Cox regression model to the analysis and modeling of the failure rate of technical devices. The objective is to recall the method of statistical analysis of such a model, to adapt it to the real–case study, and in such a way to demonstrate the flexibility of the Cox model. The goodness-of-fit of the model is tested, too, with the aid of the graphical test procedure based on generalized residuals.

Complementary analysis of the initial value problem for a system of o.d.e. modelling the immune system after vaccinations

Urszula Foryś, Norbert Żołek (2000)

Applicationes Mathematicae

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Complementary analysis of a model of the human immune system after a series of vaccinations, proposed in [7] and studied in [6], is presented. It is shown that all coordinates of every solution have at most two extremal values. The theoretical results are compared with experimental data.

Mathematical modelling of the response of breast cancer to drug therapy.

Cameron, D.A. (1997)

Journal of Theoretical Medicine

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Mathematical modelling of the interleukin-2 T-cell system: A comparative study of approaches based on ordinary and delay differential equations.

Baker, C.T.H., Bocharov, G.A., Paul, C.A.H. (1997)

Journal of Theoretical Medicine

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Spatial correlation of gene expression measures in tissue microarry core analysis.

Emily, Mathieu, Morel, Didier, Marcelpoil, Raphael, François, Olivier (2005)

Journal of Theoretical Medicine

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Modelling the effects of Paclitaxel and Cisplatin on breast and ovarian cancer.

Panetta, John Carl, Chaplain, Mark A.J., Cameron, David (2000)

Journal of Theoretical Medicine

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The onset of necrosis in a 3D cellular automaton model of EMT6 multi-cellular spheroids

Simon D. Angus, Monika J. Piotrowska (2010)

Applicationes Mathematicae

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A 3-dimensional (3D) extension to a previously reported scaled 2-dimensional Cellular Automaton (CA) model of avascular multi-cellular spheroid growth is presented and analysed for the EMT6/Ro cell line. The model outputs are found to compare favourably with reported experimentally obtained data for in vitro spheroids of the same cell line. Necrosis (unprogrammed central cell death) is observed to be delayed when compared with the experimental data. Furthermore, it is found that necrosis...

Repopulation of tumour cells during radiotherapy is doubled during treatment gaps.

Tarnawski, Rafal, Skladowski, Krzysztof, Swierniak, Andrzej, Wygoda, Andrzej, Mucha, Anna (2000)

Journal of Theoretical Medicine

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Application of Hybrid Models to Blood Cell Production in the Bone Marrow

N. Bessonov, F. Crauste, S. Fischer, P. Kurbatova, V. Volpert (2011)

Mathematical Modelling of Natural Phenomena

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A hybrid model of red blood cell production, where cells are considered as discrete objects while intra-cellular proteins and extra-cellular biochemical substances are described with continuous models, is proposed. Spatial organization and regulation of red blood cell production (erythropoiesis) are investigated. Normal erythropoiesis is simulated in two dimensions, and the influence on the output of the model of some parameters involved...