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Identifiability and estimation of pharmacokinetic parameters for the ligands of the macrophage mannose receptor

Nathalie Verdiere, Lilianne Denis-Vidal, Ghislaine Joly-Blanchard, Dominique Domurado (2005)

International Journal of Applied Mathematics and Computer Science

The aim of this paper is numerical estimation of pharmacokinetic parameters of the ligands of the macrophage mannose receptor, without knowing it a priori the values of these parameters. However, it first requires a model identifiability analysis, which is done by applying an algorithm implemented in a symbolic computation language. It is shown that this step can lead to a direct numerical estimation algorithm. In this way, a first estimate is computed from noisy simulated observations without it...

Intégration algorithmique des fonctions élémentairement transcendantes sur une courbe algébrique

J. H. Davenport (1984)

Annales de l'institut Fourier

On considère le problème de déterminer les solutions d’une équation différentielle ordinaire, dite de Risch sur une courbe algébrique. En fait une généralisation assez évidente de la méthode de Risch suffit mais elle nous permet de généraliser son algorithme d’intégration à toute extension élémentairement transcendante d’une extension algébrique des fonctions rationnelles.

Introduction to the Maple Power Tool Intpakx

Krämer, Walter (2007)

Serdica Journal of Computing

The paper has been presented at the 12th International Conference on Applications of Computer Algebra, Varna, Bulgaria, June, 2006The Maple Power Tool intpakX [24] de nes Maple types for real intervals and complex disc intervals. On the level of basic operations, intpakX includes the four basic arithmetic operators, including extended interval division as an extra function. Furthermore, there are power, square, square root, logarithm and exponential functions, a set of standard functions, union,...

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