Mathematical problems in modeling artificial heart.
Mathematical theory of improvability of production systems.
Media/psychological impact on multiple outbreaks of emerging infectious diseases.
Methods for estimating vehicle queues at a marine terminal: a computational comparison
Minimizing energy use for a road expansion in a transportation system using optimal control theory.
Model based analysis of signaling pathways
The paper is concerned with application of mathematical modeling to the analysis of signaling pathways. Two issues, deterministic modeling of gene transcription and model-driven discovery of regulatory elements, are dealt with. First, the biological background is given and the importance of the stochastic nature of biological processes is addressed. The assumptions underlying deterministic modeling are presented. Special emphasis is put on describing gene transcription. A framework for including...
Model of shell metal mould heating in the automotive industry
This article focuses on heat radiation intensity optimization on the surface of a shell metal mould. Such moulds are used in the automotive industry in the artificial leather production (the artificial leather is used, e.g., on car dashboards). The mould is heated by infrared heaters. After the required temperature is attained, the inner mould surface is sprinkled with special PVC powder. The powder melts and after cooling down it forms the artificial leather. A homogeneous temperature field of...
Model reduction methods for chaotic systems
Modeling acquaintance networks based on balance theory
An acquaintance network is a social structure made up of a set of actors and the ties between them. These ties change dynamically as a consequence of incessant interactions between the actors. In this paper we introduce a social network model called the Interaction-Based (IB) model that involves well-known sociological principles. The connections between the actors and the strength of the connections are influenced by the continuous positive and negative interactions between the actors and, vice...
Modeling and simulation of a blood pump for the development of a left ventricular assist system controller
A mathematical model describing the pressure-volume relationship of the Novacor left ventricular assist system (LVAS) was developed. The model consisted of lumped resistance, capacitance, and inductance elements with one time-varying capacitor to simulate the cyclical pressure generation of the system. The ejection and filling portions of the pump cycle were modeled with two separate functions. The corresponding model parameters were estimated by least squares fit to experimental data obtained in...
Modeling biomarker dynamics with implications for the treatment of prostate cancer.
Modeling nonlinear road traffic networks for junction control
The paper introduces a method of mathematical modeling of high scale road traffic networks, where a new special hypermatrix structure is intended to be used. The structure describes the inner-inner, inner-outer and outer-outer relations, and laws of a network area. The research examines the nonlinear equation system. The analysed model can be applied to the testing and planning of large-scale road traffic networks and the regulation of traffic systems. The elaborated model is in state space form,...
Modeling Non-Stationary Processes of Diffusion of Solute Substances in the Near-Bottom Layer ofWater Reservoirs: Variation of the Direction of Flows and Assessment of Admissible Biogenic Load
The paper is devoted to mathematical modelling and numerical computations of a nonstationary free boundary problem. The model is based on processes of molecular diffusion of some products of chemical decomposition of a solid organic substance concentrated in bottom sediments. It takes into account non-stationary multi-component and multi-stage chemical decomposition of organic substances and the processes of sorption desorption under aerobic and anaerobic conditions. Such a model allows one to...
Modeling recruitment maneuvers with a variable compliance model for pressure controlled ventilation.
Modeling the Cancer Stem Cell Hypothesis
Solid tumors and hematological cancers contain small population of tumor cells that are believed to play a critical role in the development and progression of the disease. These cells, named Cancer Stem Cells (CSCs), have been found in leukemia, myeloma, breast, prostate, pancreas, colon, brain and lung cancers. It is also thought that CSCs drive the metastatic spread of cancer. The CSC compartment features a specific and phenotypically defined cell...
Modeling the Dynamics of the Cardiovascular-respiratory System (CVRS) in Humans, a Survey
In this paper we give a survey on modeling efforts concerning the CVRS. The material we discuss is organized in accordance with modeling goals and stresses control and transport issues. We also address basic modeling approaches and discuss some of the challenges for mathematical modeling methodologies in the context of parameter estimation and model validation.
Modelling AIDS epidemic and treatment with difference equations.
Modelling, analysis and calculation of cerebral hemodynamics.
Modelling and identification of voids nucleation and growth effects in porous media plastic flow
Modelling and quasilinear control of compressor surge and rotating stall vibrations.