On the global dynamics of the cancer AIDS-related mathematical model
Konstantin E. Starkov; Corina Plata-Ante
Kybernetika (2014)
- Volume: 50, Issue: 4, page 563-579
- ISSN: 0023-5954
Access Full Article
topAbstract
topHow to cite
topStarkov, Konstantin E., and Plata-Ante, Corina. "On the global dynamics of the cancer AIDS-related mathematical model." Kybernetika 50.4 (2014): 563-579. <http://eudml.org/doc/262011>.
@article{Starkov2014,
abstract = {In this paper we examine some features of the global dynamics of the four-dimensional system created by Lou, Ruggeri and Ma in 2007 which describes the behavior of the AIDS-related cancer dynamic model in vivo. We give upper and lower ultimate bounds for concentrations of cell populations and the free HIV-1 involved in this model. We show for this dynamics that there is a positively invariant polytope and we find a few surfaces containing omega-limit sets for positive half trajectories in the positive orthant. Finally, we derive the main result of this work: sufficient conditions of ultimate cancer free behavior.},
author = {Starkov, Konstantin E., Plata-Ante, Corina},
journal = {Kybernetika},
keywords = {cancer growth model; AIDS; compact invariant set; omega-limit set; localization; ultimate cancer free dynamics; cancer growth model; AIDS; compact invariant set; omega-limit set; localization; ultimate cancer free dynamics},
language = {eng},
number = {4},
pages = {563-579},
publisher = {Institute of Information Theory and Automation AS CR},
title = {On the global dynamics of the cancer AIDS-related mathematical model},
url = {http://eudml.org/doc/262011},
volume = {50},
year = {2014},
}
TY - JOUR
AU - Starkov, Konstantin E.
AU - Plata-Ante, Corina
TI - On the global dynamics of the cancer AIDS-related mathematical model
JO - Kybernetika
PY - 2014
PB - Institute of Information Theory and Automation AS CR
VL - 50
IS - 4
SP - 563
EP - 579
AB - In this paper we examine some features of the global dynamics of the four-dimensional system created by Lou, Ruggeri and Ma in 2007 which describes the behavior of the AIDS-related cancer dynamic model in vivo. We give upper and lower ultimate bounds for concentrations of cell populations and the free HIV-1 involved in this model. We show for this dynamics that there is a positively invariant polytope and we find a few surfaces containing omega-limit sets for positive half trajectories in the positive orthant. Finally, we derive the main result of this work: sufficient conditions of ultimate cancer free behavior.
LA - eng
KW - cancer growth model; AIDS; compact invariant set; omega-limit set; localization; ultimate cancer free dynamics; cancer growth model; AIDS; compact invariant set; omega-limit set; localization; ultimate cancer free dynamics
UR - http://eudml.org/doc/262011
ER -
References
top- Boer, R. J. De, Perelson, A. S., 10.1006/jtbi.1997.0548, J. Theoret. Biol. 190 (1998), 3, 201-214. DOI10.1006/jtbi.1997.0548
- Hraba, T., Doležal, J., Čelikovský, S., 10.1016/S0171-2985(11)80169-5, Immunobiology 181 (1990), 108-118. DOI10.1016/S0171-2985(11)80169-5
- Krishchenko, A. P., 10.1016/S0898-1221(97)00130-2, Comput. Math. Appl. 34 (1997), 325-332. MR1478765DOI10.1016/S0898-1221(97)00130-2
- Krishchenko, A. P., 10.1007/s10625-006-0003-6, Differ. Equ. 41 (2005), 1669-1676. Zbl1133.34342MR2243456DOI10.1007/s10625-006-0003-6
- Krishchenko, A. P., Starkov, K. E., 10.1016/j.physleta.2005.12.104, Phys. Lett. A 353 (2006), 5, 383-388. Zbl1181.37044MR2221803DOI10.1016/j.physleta.2005.12.104
- Levy, J. A., HIV and the Pathogenesis of AIDS., Springer-Verlag, New York 1999.
- Lou, J., Ma, Z., Shao, Y., Han, L., 10.1016/j.camwa.2004.04.031, Comput. Math. Appl. 48 (2004), 9-33. Zbl1064.92027MR2086782DOI10.1016/j.camwa.2004.04.031
- Lou, J., Ruggeri, T., Tebaldi, C., 10.3934/mbe.2006.3.313, Math. Biosci. Eng. 3 (2006), 2, 313-324. MR2213522DOI10.3934/mbe.2006.3.313
- Lou, J., Ruggeri, T., Ma, Z., 10.1142/S0218339007002131, J. Biol. Systems 15 (2007), 02, 149-168. Zbl1279.92040DOI10.1142/S0218339007002131
- Perelson, A. S., Kirschner, D. E., DeBoer, R., Dynamics of HIV infection of CD4+ T cells., Math. Biosci. 114 (1993), 1, 81-125.
- Perko, L., Differential Equations an Dynamical Systems. Second edition., Springer-Verlag, New York, Berlin, Heidelberg 1996. MR1418638
- Starkov, K. E., 10.1016/j.physleta.2011.06.064, Phys. Lett. A 375 (2011), 3184-3187. Zbl1252.83129MR2824198DOI10.1016/j.physleta.2011.06.064
- Starkov, K. E., Coria, L. N., Global dynamics of the Kirschner-Panetta model for the tumor immunotherapy., Nonlinear Anal. Real World Appl. 14 (2013), 1425-1433. MR3004510
- Starkov, K. E., Pogromsky, A. Y., 10.1142/S021812741350020X, Int. J. Bifur. Chaos Appl. Sci. Engrg. 23 (2013). Zbl1270.34137MR3041470DOI10.1142/S021812741350020X
- Starkov, K. E., Gamboa, D., 10.1002/mma.3023, Math. Methods Appl. Sci. (2013). DOI10.1002/mma.3023
- Starkov, K. E., Krishchenko, A. P., 10.1016/j.cnsns.2013.09.023, Commun. Nonlin. Sci. Numer. Simul. 19 (2014), 1486-1495. MR3128676DOI10.1016/j.cnsns.2013.09.023
- Starkov, K. E., Villegas, A., 10.1142/S0218127414500205, Int. J. Bifur. Chaos Appl. Sci. Engrg. 24 (2014). MR3187160DOI10.1142/S0218127414500205
- Valle, P. A., Coria, L. N., Starkov, K. E., Estudio de la dinamica global para un modelo de evasion-inmune de un tumor cancerigeno., Comp. y Sistemas, accepted.
- Wang, L., Li, M. Y., 10.1016/j.mbs.2005.12.026, Math. Biosci. 200 (2006), 44-57. Zbl1086.92035MR2211927DOI10.1016/j.mbs.2005.12.026
- Wen, Q., Lou, J., 10.1007/s11587-009-0048-y, Ric. Mat. 58 (2009), 1, 77-90. Zbl1184.34058MR2507794DOI10.1007/s11587-009-0048-y
NotesEmbed ?
topTo embed these notes on your page include the following JavaScript code on your page where you want the notes to appear.