### A class age-structured HIV/AIDS model with impulsive drug-treatment strategy.

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A decision analytical model is presented and analysed to assess the effectiveness and cost-effectiveness of routine vaccination against varicella and herpes-zoster, or shingles. These diseases have as common aetiological agent the varicella-zoster virus (VZV). Zoster can more likely occur in aged people with declining cell-mediated immunity. The general concern is that universal varicella vaccination might lead to more cases of zoster: with more...

About twenty five years ago the first discrete mathematical model of the immune system was proposed. It was very simple and stylized. Later, many other computational models have been proposed each one adding a certain level of sophistication and detail to the description of the system. One of these, the Celada-Seiden model published back in 1992, was already mature at its birth, setting apart from the topic-specific nature of the other models. This...

The CDC launched the National Plan to Eliminate Syphilis from the USA in October 1999 [4]. In order to reach this goal, a good understanding of the transmission dynamics of the disease is necessary. Based on a SIRS model Breban et al. [3] provided some evidence that supports the feasibility of the plan proving that no recurring outbreaks should occur for syphilis. We study in this work a syphilis model that includes partial...

The paper is concerned with an extension of the classical relation between the flame speed and the curvature-flow stretch, valid only for high Lewis numbers (diffusively stable flames). At low Lewis numbers the corresponding flame-flow system suffers short-wavelength instability, making the associated initial value problem ill-posed. In this study the difficulty is resolved by incorporation of higher-order effects. As a result one ends up with a reduced model based on a coupled system of second-order...

A two dimensional stochastic differential equation is suggested as a stochastic model for the Kermack–McKendrick epidemics. Its strong (weak) existence and uniqueness and absorption properties are investigated. The examples presented in Section 5 are meant to illustrate possible different asymptotics of a solution to the equation.

BackgroundIndependence models among variables is one of the most relevant topics in epidemiology, particularly in molecular epidemiology for the study of gene-gene and gene-environment interactions. They have been studied using three main kinds of analysis: regression analysis, data mining approaches and Bayesian model selection. Recently, methods of algebraic statistics have been extensively used for applications to biology. In this paper we present...

Global existence results and long time behavior are provided for a mathematical model describing the propagation of Feline Panleucopenia Virus (FPLV) within a domestic cat population; two transmission modes are involved: a direct one from infective cats to susceptible ones, and an indirect one from the contaminated environment to susceptible cats. A more severe impact of the virus on young cats requires an age-structured model.

We study a mathematical model which was originally suggested by Greenhalgh and Das and takes into account the delay in the recruitment of infected persons. The stability of the equilibria are also discussed. In addition, we show that the introduction of a time delay in the transmission term can destabilize the system and periodic solutions can arise by Hopf bifurcation.

A possible control strategy against the spread of an infectious disease is the treatment with antimicrobials that are given prophylactically to those that had contact with an infective person. The treatment continues until recovery or until it becomes obvious that there was no infection in the first place. The model considers susceptible, treated uninfected exposed, treated infected, (untreated) infectious, and recovered individuals. The overly optimistic assumptions are made that treated uninfected...