Caratterizzazione delle subunità biosintetiche H-6S e H-7S della tireoglobulina di ratto
The heterogeneous component 3-8 S, labeled with H-leucine after incubation of rat thyroid hemilobes in vitro, has been fractionated by means of several centrifugations in sucrose density gradients. Two labeled components, the H-6 S and the H-7 S proteins have been isolated in ultracentrifugally homogeneous form. Their relations with 19 S thyroglobulin from the same species have been ascertained by means of immunologic criteria. The molecular weight of the two proteins, determined by filtration through...