All two dimensions links are null homotopic.
We study self-homotopy equivalences and diffeomorphisms of the (n+1)-dimensional manifold X= #p(S1 x Sn) for any n ≥ 3. Then we completely determine the group of pseudo-isotopy classes of homeomorphisms of X and extend to dimension n well-known theorems due to F. Laudenbach and V. Poenaru (1972,1973), and J. M. Montesinos (1979).