In proteomics study, Imaging Mass Spectrometry (IMS) is an emerging and very promising new technique for protein analysis from intact biological tissues. Though it has shown great potential and is very promising for rapid mapping of protein localization and the detection of sizeable differences in protein expression, challenges remain in data processing due to the difficulty of high dimensionality and the fact that the number of input variables in...

N. N. Cencov wrote a commentary chapter included in the Appendix of the Russian translation of the Devroye and Györfi book [15] collecting some arguments supporting the $L_1$ view of density estimation. The Cencov’s work is available in Russian only and it hasn’t been translated, so late Igor Vajda decided to translate the Cencov’s paper and to add some remarks on the occasion of organizing the session “25 Years of the $L_1$ Density Estimation” at the Prague Stochastics 2010 Symposium. In this paper we...