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Comparative Study of a Solid Film Dewetting in an Attractive Substrate Potentials with the Exponential and the Algebraic Decay

M. Khenner (2008)

Mathematical Modelling of Natural Phenomena

We compare dewetting characteristics of a thin nonwetting solid film in the absence of stress, for two models of a wetting potential: the exponential and the algebraic. The exponential model is a one-parameter (r) model, and the algebraic model is a two-parameter (r, m) model, where r is the ratio of the characteristic wetting length to the height of the unperturbed film, and m is the exponent of h (film height) in a smooth function that interpolates the system's surface energy above and below...

Mathematically Modelling The Dissolution Of Solid Dispersions

Meere, Martin, McGinty, Sean, Pontrelli, Giuseppe (2017)

Proceedings of Equadiff 14

A solid dispersion is a dosage form in which an active ingredient (a drug) is mixed with at least one inert solid component. The purpose of the inert component is usually to improve the bioavailability of the drug. In particular, the inert component is frequently chosen to improve the dissolution rate of a drug that is poorly soluble in water. The construction of reliable mathematical models that accurately describe the dissolution of solid dispersions would clearly assist with their rational design....

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