Let $(R,𝔪)$ be a complete local ring, $𝔞$ an ideal of $R$ and $N$ and $L$ two Matlis reflexive $R$-modules with $\mathrm{Supp}\left(L\right)\subseteq V\left(𝔞\right)$. We prove that if $M$ is a finitely generated $R$-module, then ${\mathrm{Ext}}_R^i(L,H_{𝔞}^j(M,N))$ is Matlis reflexive for all $i$ and $j$ in the following cases: (a) $\dim R/𝔞=1$; (b) $\mathrm{cd}\left(𝔞\right)=1$; where $\mathrm{cd}$ is the cohomological dimension of $𝔞$ in $R$; (c) $\dim R\le 2$. In these cases we also prove that the Bass numbers of $H_{𝔞}^j(M,N)$ are finite.