We consider the existence of at least one positive solution to the dynamic boundary value problem $$\begin{array}{cccc}\hfill -y^{\Delta \Delta }\left(t\right)& =\lambda f(t,y\left(t\right))\text{,}t\in {[0,T]}_{𝕋}y\left(0\right)\hfill & \hfill ={\int }_{{\tau }_1}^{{\tau }_2}{F}_1(s,y\left(s\right))\Delta sy\left({\sigma }^2\left(T\right)\right)& ={\int }_{{\tau }_3}^{{\tau }_4}{F}_2(s,y\left(s\right))\Delta s,\hfill \end{array}$$ where $𝕋$ is an arbitrary time scale with $0<{\tau }_1<{\tau }_2<{\sigma }^2\left(T\right)$ and $0<{\tau }_3<{\tau }_4<{\sigma }^2\left(T\right)$ satisfying ${\tau }_1$, ${\tau }_2$, ${\tau }_3$, ${\tau }_4\in 𝕋$, and where the boundary conditions at $t=0$ and $t={\sigma }^2\left(T\right)$ can be both nonlinear and nonlocal. This extends some recent results on second-order semipositone dynamic boundary value problems, and we illustrate these extensions with some examples.