We investigate the amenability and its related homological notions for a class of $I\times I$-upper triangular matrix algebra, say $\mathrm{UP}(I,A)$, where $A$ is a Banach algebra equipped with a nonzero character. We show that $\mathrm{UP}(I,A)$ is pseudo-contractible (amenable) if and only if $I$ is singleton and $A$ is pseudo-contractible (amenable), respectively. We also study pseudo-amenability and approximate biprojectivity of $\mathrm{UP}(I,A)$.