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Reconstruction of map projection, its inverse and re-projection

Tomáš Bayer, Milada Kočandrlová (2018)

Applications of Mathematics

This paper focuses on the automatic recognition of map projection, its inverse and re-projection. Our analysis leads to the unconstrained optimization solved by the hybrid BFGS nonlinear least squares technique. The objective function is represented by the squared sum of the residuals. For the map re-projection the partial differential equations of the inverse transformation are derived. They can be applied to any map projection. Illustrative examples of the stereographic and globular Nicolosi projections...

Regulatory network of drug-induced enzyme production: parameter estimation based on the periodic dosing response measurement

Papáček, Štěpán, Lynnyk, Volodymyr, Rehák, Branislav (2021)

Programs and Algorithms of Numerical Mathematics

The common goal of systems pharmacology, i.e. systems biology applied to the field of pharmacology, is to rely less on trial and error in designing an input-output systems, e.g. therapeutic schedules. In this paper we present, on the paradigmatic example of a regulatory network of drug-induced enzyme production, the further development of the study published by Duintjer Tebbens et al. (2019) in the Applications of Mathematics. Here, the key feature is that the nonlinear model in form of an ODE system...

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