Medical image – based computational model of pulsatile flow in saccular aneurisms

Stéphanie Salmon; Marc Thiriet; Jean-Frédéric Gerbeau

ESAIM: Mathematical Modelling and Numerical Analysis (2010)

  • Volume: 37, Issue: 4, page 663-679
  • ISSN: 0764-583X

Abstract

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Saccular aneurisms, swelling of a blood vessel, are investigated in order (i) to estimate the development risk of the wall lesion, before and after intravascular treatment, assuming that the pressure is the major factor, and (ii) to better plan medical interventions. Numerical simulations, using the finite element method, are performed in three-dimensional aneurisms. Computational meshes are derived from medical imaging data to take into account both between-subject and within-subject anatomical variability of the diseased vessel segment. The 3D reconstruction is associated with a faceted surface. A geometrical model is then obtained to be finally meshed for a finite element use. The pulsatile flow of incompressible Newtonian blood is illustrated by numerical simulations carried out in two saccular aneurism types, a side- and a terminal-aneurism. High pressure zones are observed in the aneurism cavity, especially in the terminal one.

How to cite

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Salmon, Stéphanie, Thiriet, Marc, and Gerbeau, Jean-Frédéric. "Medical image – based computational model of pulsatile flow in saccular aneurisms." ESAIM: Mathematical Modelling and Numerical Analysis 37.4 (2010): 663-679. <http://eudml.org/doc/194184>.

@article{Salmon2010,
abstract = { Saccular aneurisms, swelling of a blood vessel, are investigated in order (i) to estimate the development risk of the wall lesion, before and after intravascular treatment, assuming that the pressure is the major factor, and (ii) to better plan medical interventions. Numerical simulations, using the finite element method, are performed in three-dimensional aneurisms. Computational meshes are derived from medical imaging data to take into account both between-subject and within-subject anatomical variability of the diseased vessel segment. The 3D reconstruction is associated with a faceted surface. A geometrical model is then obtained to be finally meshed for a finite element use. The pulsatile flow of incompressible Newtonian blood is illustrated by numerical simulations carried out in two saccular aneurism types, a side- and a terminal-aneurism. High pressure zones are observed in the aneurism cavity, especially in the terminal one. },
author = {Salmon, Stéphanie, Thiriet, Marc, Gerbeau, Jean-Frédéric},
journal = {ESAIM: Mathematical Modelling and Numerical Analysis},
keywords = {3D surface reconstruction; finite element method; medical images; mesh generation; Navier–Stokes equations.; finite element method; medical images; Navier-Stokes equations},
language = {eng},
month = {3},
number = {4},
pages = {663-679},
publisher = {EDP Sciences},
title = {Medical image – based computational model of pulsatile flow in saccular aneurisms},
url = {http://eudml.org/doc/194184},
volume = {37},
year = {2010},
}

TY - JOUR
AU - Salmon, Stéphanie
AU - Thiriet, Marc
AU - Gerbeau, Jean-Frédéric
TI - Medical image – based computational model of pulsatile flow in saccular aneurisms
JO - ESAIM: Mathematical Modelling and Numerical Analysis
DA - 2010/3//
PB - EDP Sciences
VL - 37
IS - 4
SP - 663
EP - 679
AB - Saccular aneurisms, swelling of a blood vessel, are investigated in order (i) to estimate the development risk of the wall lesion, before and after intravascular treatment, assuming that the pressure is the major factor, and (ii) to better plan medical interventions. Numerical simulations, using the finite element method, are performed in three-dimensional aneurisms. Computational meshes are derived from medical imaging data to take into account both between-subject and within-subject anatomical variability of the diseased vessel segment. The 3D reconstruction is associated with a faceted surface. A geometrical model is then obtained to be finally meshed for a finite element use. The pulsatile flow of incompressible Newtonian blood is illustrated by numerical simulations carried out in two saccular aneurism types, a side- and a terminal-aneurism. High pressure zones are observed in the aneurism cavity, especially in the terminal one.
LA - eng
KW - 3D surface reconstruction; finite element method; medical images; mesh generation; Navier–Stokes equations.; finite element method; medical images; Navier-Stokes equations
UR - http://eudml.org/doc/194184
ER -

References

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