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In this paper, we introduce a set of methods for processing and analyzing long time series of 3D images representing embryo evolution. The images are obtained by in vivo scanning using a confocal microscope where one of the channels represents the cell nuclei and the other one the cell membranes. Our image processing chain consists of three steps: image filtering, object counting (center detection) and segmentation. The corresponding methods are based on numerical solution of nonlinear PDEs, namely...
The image's restoration is an essential step in medical imaging.
Several Filters are developped to remove noise, the most interesting
are filters who permits to denoise the image preserving semantically
important structures. One class of recent adaptive denoising methods
is the nonlinear Partial Differential Equations who knows currently a
significant success. This work deals with mathematical study for a
proposed nonlinear evolution partial differential equation for image
processing. The existence...
The role of relaxation oscillator models in application fields such as modeling dynamic systems and image analysis is discussed. A short review of the Van der Pol, Wilson-Cowan and Terman-Wang relaxation oscillators is given. The key property of such nonlinear oscillators, i.e., the oscillator phase shift (called the Phase Response Curve) as a result of external pulse stimuli is indicated as a fundamental mechanism to achieve and sustain synchrony in networks of coupled oscillators. It is noted...
This work presents new application of the random field theory in medical imaging. Results from both integral geometry and random field theory can be used to detect locations with significantly increased radiotracer uptake in images from positron emission tomography (PET). The assumptions needed to use these results are verified on a set of real and simulated phantom images. The proposed method of detecting activation (locations with increased radiotracer concentration) is used to quantify the quality...
We develop a method for counting number of cells and extraction of approximate cell centers in 2D and 3D images of early stages of the zebra-fish embryogenesis. The approximate cell centers give us the starting points for the subjective surface based cell segmentation. We move in the inner normal direction all level sets of nuclei and membranes images by a constant speed with slight regularization of this flow by the (mean) curvature. Such multi- scale evolutionary process is represented by a geometrical...
This paper is concerned with the coupling of two models for the propagation of particles in scattering media. The first model is a linear transport equation of Boltzmann type posed in the phase space (position and velocity). It accurately describes the physics but is very expensive to solve. The second model is a diffusion equation posed in the physical space. It is only valid in areas of high scattering, weak absorption, and smooth physical coefficients, but its numerical solution is much cheaper...
This paper is concerned with the coupling of two models for the
propagation of particles in scattering media. The first model is a
linear transport equation of Boltzmann type posed in the phase space
(position and velocity). It accurately describes the physics but is
very expensive to solve. The second model is a diffusion equation
posed in the physical space. It is only valid in areas of high
scattering, weak absorption, and smooth physical coefficients, but
its numerical solution is...
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