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Comparison of six models of antiangiogenic therapy

Andrzej Świerniak (2009)

Applicationes Mathematicae

Six models of antiangiogenic therapy are compared and analyzed from control-theoretic point of view. All of them consist of a model of tumor growth bounded by the capacity of a vascular network developed by the tumor in the process of angiogenesis and different models of dynamics of this network, and are based on the idea proposed by Hahnfeldt et al. Moreover, we analyse optimal control problems resulting from their use in treatment protocol design.

Competitive Exclusion in a Discrete Stage-Structured Two Species Model

A. S. Ackleh, P. Zhang (2009)

Mathematical Modelling of Natural Phenomena

We develop a stage-structured model that describes the dynamics of two competing species each of which have sexual and clonal reproduction. This is typical of many plants including irises. We first analyze the dynamical behavior of a single species model. We show that when the inherent net reproductive number is smaller than one then the population will go to extinction and if it is larger than one then an interior equilibrium exists and it is globally asymptotically stable. Then we analyze...

Could changes in national tuberculosis vaccination policies be ill-informed ?

D.J. Gerberry, F.A. Milner (2012)

Mathematical Modelling of Natural Phenomena

National policies regarding the BCG vaccine for tuberculosis vary greatly throughout the international community and several countries are currently considering discontinuing universal vaccination. Detractors of BCG point to its uncertain effectiveness and its interference with the detection and treatment of latent tuberculosis infection (LTBI). In order to quantify the trade-off between vaccination and treatment of LTBI, a mathematical model was designed and calibrated to data from Brazil, Ghana,...

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