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Generalization of the Kermack-McKendrick SIR Model to a Patchy Environment for a Disease with Latency

J. Li, X. Zou (2009)

Mathematical Modelling of Natural Phenomena

In this paper, with the assumptions that an infectious disease has a fixed latent period in a population and the latent individuals of the population may disperse, we reformulate an SIR model for the population living in two patches (cities, towns, or countries etc.), which is a generalization of the classic Kermack-McKendrick SIR model. The model is given by a system of delay differential equations with a fixed delay accounting for the latency and non-local terms caused by the mobility of the...

Global attractivity of the equilibrium of a nonlinear difference equation

John R. Graef, C. Qian (2002)

Czechoslovak Mathematical Journal

The authors consider the nonlinear difference equation x n + 1 = α x n + x n - k f ( x n - k ) , n = 0 , 1 , . 1 where α ( 0 , 1 ) , k { 0 , 1 , } and f C 1 [ [ 0 , ) , [ 0 , ) ] ( 0 ) with f ' ( x ) < 0 . They give sufficient conditions for the unique positive equilibrium of (0.1) to be a global attractor of all positive solutions. The results here are somewhat easier to apply than those of other authors. An application to a model of blood cell production is given.

Global stability of steady solutions for a model in virus dynamics

Hermano Frid, Pierre-Emmanuel Jabin, Benoît Perthame (2003)

ESAIM: Mathematical Modelling and Numerical Analysis - Modélisation Mathématique et Analyse Numérique

We consider a simple model for the immune system in which virus are able to undergo mutations and are in competition with leukocytes. These mutations are related to several other concepts which have been proposed in the literature like those of shape or of virulence – a continuous notion. For a given species, the system admits a globally attractive critical point. We prove that mutations do not affect this picture for small perturbations and under strong structural assumptions. Based on numerical...

Global Stability of Steady Solutions for a Model in Virus Dynamics

Hermano Frid, Pierre-Emmanuel Jabin, Benoît Perthame (2010)

ESAIM: Mathematical Modelling and Numerical Analysis

We consider a simple model for the immune system in which virus are able to undergo mutations and are in competition with leukocytes. These mutations are related to several other concepts which have been proposed in the literature like those of shape or of virulence – a continuous notion. For a given species, the system admits a globally attractive critical point. We prove that mutations do not affect this picture for small perturbations and under strong structural assumptions. Based on numerical...

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