Spatial correlation of gene expression measures in tissue microarry core analysis.
We discuss the prediction of a spatial variable of a multivariate mark composed of both dependent and explanatory variables. The marks are location-dependent and they are attached to a point process. We assume that the marks are assigned independently, conditionally on an unknown underlying parametric field. We compare (i) the classical non-parametric Nadaraya-Watson kernel estimator based on the dependent variable (ii) estimators obtained under an assumption of local parametric model where explanatory...
Spatial planar indices have become a useful tool to analyze patterns of points. Despite that, no simulation study has been reported in literature in order to analyze the behaviour of these quantities under different pattern structures. We present here an extensive Monte Carlo simulation study focused on two important indices: the Index of Dispersion and the Index of Cluster Size, usually used to detect lack of homogeneity in a spatial point model. Finally, an application is also presented.
The paper deals with Cox point processes in time and space with Lévy based driving intensity. Using the generating functional, formulas for theoretical characteristics are available. Because of potential applications in biology a Cox process sampled by a curve is discussed in detail. The filtering of the driving intensity based on observed point process events is developed in space and time for a parametric model with a background driving compound Poisson field delimited by special test sets. A...
Spatial structures in the form of point patterns arise in many different contexts, and in most of them the key goal concerns the detection and recognition of the underlying spatial pattern. Particularly interesting is the case of pattern analysis with replicated data in two or more experimental groups. This paper compares design-based and model-based approaches to the analysis of this kind of spatial data. Basic questions about pattern detection concern estimating the properties of the underlying...