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We review the optimal design of an arterial bypass graft following either a (i) boundary optimal control approach, or a (ii) shape optimization formulation. The main focus is quantifying and treating the uncertainty in the residual flow when the hosting artery is not completely occluded, for which the worst-case in terms of recirculation effects is inferred to correspond to a strong orifice flow through near-complete occlusion.A worst-case optimal control approach is applied to the steady Navier-Stokes...
For a shape optimization problem second derivatives are investigated, obtained by a special approach for the description of the boundary variation and the use of a potential ansatz for the state. The natural embedding of the problem in a Banach space allows the application of a standard differential calculus in order to get second derivatives by a straight forward "repetition of differentiation". Moreover, by using boundary value characerizations for more regular data, a complete boundary integral...
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