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Globalization of SQP-Methods in Control of the Instationary Navier-Stokes Equations

Michael Hintermüller, Michael Hinze (2010)

ESAIM: Mathematical Modelling and Numerical Analysis

A numerically inexpensive globalization strategy of sequential quadratic programming methods (SQP-methods) for control of the instationary Navier Stokes equations is investigated. Based on the proper functional analytic setting a convergence analysis for the globalized method is given. It is argued that the a priori formidable SQP-step can be decomposed into linear primal and linear adjoint systems, which is amenable for existing CFL-software. A report on a numerical test demonstrates the feasibility...

Integrated Design of an Active Flow Control System Using a Time-Dependent Adjoint Method

E.J. Nielsen, W.T. Jones (2011)

Mathematical Modelling of Natural Phenomena

An exploratory study is performed to investigate the use of a time-dependent discrete adjoint methodology for design optimization of a high-lift wing configuration augmented with an active flow control system. The location and blowing parameters associated with a series of jet actuation orifices are used as design variables. In addition, a geometric parameterization scheme is developed to provide a compact set of design variables describing the wing...

On superlinear multiplier update methods for partial augmented Lagrangian techniques.

Eugenio Mijangos (2002)

Qüestiió

The minimization of a nonlinear function with linear and nonlinear constraints and simple bounds can be performed by minimizing an augmented Lagrangian function, including only the nonlinear constraints. This procedure is particularly interesting in case that the linear constraints are flow conservation equations, as there exist efficient techniques to solve nonlinear network problems. It is then necessary to estimate their multipliers, and variable reduction techniques can be used to carry out...

Optimal control of linear bottleneck problems

M. Bergounioux, F. Troeltzsch (2010)

ESAIM: Control, Optimisation and Calculus of Variations

The regularity of Lagrange multipliers for state-constrained optimal control problems belongs to the basic questions of control theory. Here, we investigate bottleneck problems arising from optimal control problems for PDEs with certain mixed control-state inequality constraints. We show how to obtain Lagrange multipliers in Lp spaces for linear problems and give an application to linear parabolic optimal control problems.

Optimisation of time-scheduled regimen for anti-cancer drug infusion

Claude Basdevant, Jean Clairambault, Francis Lévi (2005)

ESAIM: Mathematical Modelling and Numerical Analysis - Modélisation Mathématique et Analyse Numérique

The chronotherapy concept takes advantage of the circadian rhythm of cells physiology in maximising a treatment efficacy on its target while minimising its toxicity on healthy organs. The object of the present paper is to investigate mathematically and numerically optimal strategies in cancer chronotherapy. To this end a mathematical model describing the time evolution of efficiency and toxicity of an oxaliplatin anti-tumour treatment has been derived. We then applied an optimal control technique...

Optimisation of time-scheduled regimen for anti-cancer drug infusion

Claude Basdevant, Jean Clairambault, Francis Lévi (2010)

ESAIM: Mathematical Modelling and Numerical Analysis

The chronotherapy concept takes advantage of the circadian rhythm of cells physiology in maximising a treatment efficacy on its target while minimising its toxicity on healthy organs. The object of the present paper is to investigate mathematically and numerically optimal strategies in cancer chronotherapy. To this end a mathematical model describing the time evolution of efficiency and toxicity of an oxaliplatin anti-tumour treatment has been derived. We then applied an optimal control...

Variational inequalities in plasticity with strain-hardening - equilibrium finite element approach

Zdeněk Kestřánek (1986)

Aplikace matematiky

The incremental finite element method is applied to find the numerical solution of the plasticity problem with strain-hardening. Following Watwood and Hartz, the stress field is approximated by equilibrium triangular elements with linear functions. The field of the strain-hardening parameter is considered to be piecewise linear. The resulting nonlinear optimization problem with constraints is solved by the Lagrange multipliers method with additional variables. A comparison of the results obtained...

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