We consider the Hausdorff metric on the space of compact convex subsets of a proper, geodesically complete metric space of globally non-positive Busemann curvature in which geodesics do not split, and characterize their surjective isometries. Moreover, an analogous characterization of the surjective isometries of the space of compact subsets of a proper, uniquely geodesic, geodesically complete metric space in which geodesics do not split is given.