A Dvoretzky-Kiefer-Wolfowitz type inequality for the Kaplan-Meier estimator
A sensitivity analysis for causal parameters in structural proportional hazards models.
Deviations from assigned treatment occur often in clinical trials. In such a setting, the traditional intent-to-treat analysis does not measure biological efficacy but rather programmatic effectiveness. For all-or-nothing compliance situation, Loeys and Goetghebeur (2003) recently proposed a Structural Proportional Hazards method. It allows for casual estimation in the complier subpopulation provided the exclusion restriction holds: randomization per se has no effect unless exposure has changed....
Additive hazards regression with case-cohort sampled current status data
In a case-cohort design, covariate histories are measured only on cases and a subcohort that is randomly selected from the entire cohort. This design has been widely used in large epidemiologic studies, especially when the exposures of interest are expensive to assemble for all the subjects. In this paper, we propose statistical procedures for analyzing case-cohort sampled current status data under the additive hazards model. Asymptotical properties of the proposed estimator are described and we...
Análisis de duración mediante un modelo lineal generalizado semiparamétrico.
Aitkin y Clayton (1980) proponen el análisis de modelos de duración mediante modelos lineales generalizados. En este trabajo extendemos esta metodología permitiendo que el efecto de alguna de las variables explicativas pueda no ser especificado. Así, el modelo propuesto es un modelo lineal generalizado semiparamétrico, con una componente paramétrica donde se especifica la forma funcional concreta del efecto de las variables explicativas sobre la duración, y una componente no paramétrica donde recogemos...
Analytical bootstrap methods for censored data.
Aspects of analysis of multivariate failure time data.
Multivariate failure time data arise in various forms including recurrent event data when individuals are followed to observe the sequence of occurrences of a certain type of event; correlated failure time when an individual is followed for the occurrence of two or more types of events for which the individual is simultaneously at risk, or when distinct individuals have depending event times; or more complicated multistate processes where individuals may move among a number of discrete states over...
Assessing influence in survival data with a cured fraction and covariates.
Diagnostic methods have been an important tool in regression analysis to detect anomalies, such as departures from error assumptions and the presence of outliers and influential observations with the fitted models. Assuming censored data, we considered a classical analysis and Bayesian analysis assuming no informative priors for the parameters of the model with a cure fraction. A Bayesian approach was considered by using Markov Chain Monte Carlo Methods with Metropolis-Hasting algorithms steps to...