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Mathematical modeling of antigenicity for HIV dynamics

François Dubois, Hervé V.J. Le Meur, Claude Reiss (2010)

MathematicS In Action

This contribution is devoted to a new model of HIV multiplication motivated by the patent of one of the authors. We take into account the antigenic diversity through what we define “antigenicity”, whether of the virus or of the adapted lymphocytes. We model the interaction of the immune system and the viral strains by two processes. On the one hand, the presence of a given viral quasi-species generates antigenically adapted lymphocytes. On the other hand, the lymphocytes kill only viruses for which...

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