This paper presents a derivation of the Rayleigh- Betti reciprocity relation for layered curved composite beams with interlayer slip. The principle of minimum of potential energy is also formulated for two-layer curved composite beams and its applications are illustrated by numerical examples. The solution of the presented problems are obtained by the Ritz method. The applications of the Rayleigh-Betti reciprocity relation proven are illustrated by some examples.