Nonlinear filtering of oscillatory measurements in cardiovascular applications.
Numerical solutions of a fractional predator-prey system.
On characterization of the solution set in case of generalized semiflow
In the paper, a possible characterization of a chaotic behavior for the generalized semiflows in finite time is presented. As a main result, it is proven that under specific conditions there is at least one trajectory of generalized semiflow, which lies inside an arbitrary covering of the solution set. The trajectory mutually connects each subset of the covering. A connection with symbolic dynamical systems is mentioned and a possible numerical method of analysis of dynamical behavior is outlined....
On circle map coupled map lattice.
On the anti–synchronization detection for the generalized Lorenz system and its applications to secure encryption
In this paper, a modified version of the Chaos Shift Keying (CSK) scheme for secure encryption and decryption of data will be discussed. The classical CSK method determines the correct value of binary signal through checking which initially unsynchronized system is getting synchronized. On the contrary, the new anti-synchronization CSK (ACSK) scheme determines the wrong value of binary signal through checking which already synchronized system is loosing synchronization. The ACSK scheme is implemented...
On the fractality of the biological tree-like structures.
On the Mathematical Modelling of Microbial Growth: Some Computational Aspects
We propose a new approach to the mathematical modelling of microbial growth. Our approach differs from familiar Monod type models by considering two phases in the physiological states of the microorganisms and makes use of basic relations from enzyme kinetics. Such an approach may be useful in the modelling and control of biotechnological processes, where microorganisms are used for various biodegradation purposes and are often put under extreme inhibitory conditions. Some computational experiments are...
On the well posedness and refined estimates for the global attractor of the TYC model.
Optimisation of time-scheduled regimen for anti-cancer drug infusion
The chronotherapy concept takes advantage of the circadian rhythm of cells physiology in maximising a treatment efficacy on its target while minimising its toxicity on healthy organs. The object of the present paper is to investigate mathematically and numerically optimal strategies in cancer chronotherapy. To this end a mathematical model describing the time evolution of efficiency and toxicity of an oxaliplatin anti-tumour treatment has been derived. We then applied an optimal control technique...
Optimisation of time-scheduled regimen for anti-cancer drug infusion
The chronotherapy concept takes advantage of the circadian rhythm of cells physiology in maximising a treatment efficacy on its target while minimising its toxicity on healthy organs. The object of the present paper is to investigate mathematically and numerically optimal strategies in cancer chronotherapy. To this end a mathematical model describing the time evolution of efficiency and toxicity of an oxaliplatin anti-tumour treatment has been derived. We then applied an optimal control...
Pathway complexity of model virus capsid assembly systems.
Permanence and global attractivity of a discrete two-prey one-predator model with infinite delay.
Permanence and periodic solution of predator-prey system with holling type functional response and impulses.
Persistence in ratio-dependent models of consumer-resource dynamics.
Population dynamics of Bithynia tentaculata
Population Dynamics of Grayling: Modelling Temperature and Discharge Effects
We propose a matrix population modelling approach in order to describe the dynamics of a grayling (Thymallus thymallus, L. 1758) population living in the Ain river (France). We built a Leslie like model, which integrates the climate changes in terms of temperature and discharge. First, we show how temperature and discharge can be related to life history traits like survival and reproduction. Second, we show how to use the population model to precisely examine the life cycle of grayling : estimated...
Positivity and contractivity in the dynamics of clusters’ splitting with derivative of fractional order
Classical models of clusters’ fission have failed to fully explain strange phenomenons like the phenomenon of shattering (Ziff et al., 1987) and the sudden appearance of infinitely many particles in some systems with initial finite particles number. Furthermore, the bounded perturbation theorem presented in (Pazy, 1983) is not in general true in solution operators theory for models of fractional order γ (with 0 < γ ≤ 1). In this article, we introduce and study a model that can be understood as...
Pre-symptomatic Influenza Transmission, Surveillance, and School Closings: Implications for Novel Influenza A (H1N1)
Early studies of the novel swine-origin 2009 influenza A (H1N1) epidemic indicate clinical attack rates in children much higher than in adults. Non-medical interventions such as school closings are constrained by their large socio-economic costs. Here we develop a mathematical model to ascertain the roles of pre-symptomatic influenza transmission as well as symptoms surveillance of children to assess the utility of school closures. Our model analysis...
Properties of a singular value decomposition based dynamical model of gene expression data
Recently, data on multiple gene expression at sequential time points were analyzed using the Singular Value Decomposition (SVD) as a means to capture dominant trends, called characteristic modes, followed by the fitting of a linear discrete-time dynamical system in which the expression values at a given time point are linear combinations of the values at a previous time point. We attempt to address several aspects of the method. To obtain the model, we formulate a nonlinear optimization problem...
Rapid Emergence of Co-colonization with Community-acquired and Hospital-Acquired Methicillin-Resistant Staphylococcus aureus Strains in the Hospital Setting
Background: Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA), a novel strain of MRSA, has recently emerged and rapidly spread in the community. Invasion into the hospital setting with replacement of the hospital-acquired MRSA (HA-MRSA) has also been documented. Co-colonization with both CA-MRSA and HA-MRSA would have important clinical implications given differences in antimicrobial susceptibility profiles and the potential...