Regularities in Congruential Random Number Generators.
The chemical master equation is a fundamental equation in chemical kinetics. It underlies the classical reaction-rate equations and takes stochastic effects into account. In this paper we give a simple argument showing that the solutions of a large class of chemical master equations are bounded in weighted ℓ1-spaces and possess high-order moments. This class includes all equations in which no reactions between two or more already present molecules and further external reactants occur that add mass...
The numerical solution of ill-posed problems requires suitable regularization techniques. One possible option is to consider time integration methods to solve the Showalter differential equation numerically. The stopping time of the numerical integrator corresponds to the regularization parameter. A number of well-known regularization methods such as the Landweber iteration or the Levenberg-Marquardt method can be interpreted as variants of the Euler method for solving the Showalter differential...
The common goal of systems pharmacology, i.e. systems biology applied to the field of pharmacology, is to rely less on trial and error in designing an input-output systems, e.g. therapeutic schedules. In this paper we present, on the paradigmatic example of a regulatory network of drug-induced enzyme production, the further development of the study published by Duintjer Tebbens et al. (2019) in the Applications of Mathematics. Here, the key feature is that the nonlinear model in form of an ODE system...
Hard clamped and hard simply supported elastic plate is considered. The mixed finite element analysis combined with some interpolation, proposed by Brezzi, Fortin and Stenberg, is extended to the case of variable thickness and anisotropic material.
A phase field approach for structural topology optimization which allows for topology changes and multiple materials is analyzed. First order optimality conditions are rigorously derived and it is shown via formally matched asymptotic expansions that these conditions converge to classical first order conditions obtained in the context of shape calculus. We also discuss how to deal with triple junctions where e.g. two materials and the void meet. Finally, we present several numerical results for...
NURBS (Non-Uniform Rational B-Splines) belong to special approximation curves and surfaces which are described by control points with weights and B-spline basis functions. They are often used in modern areas of computer graphics as free-form modelling, modelling of processes. In literature, NURBS surfaces are often called tensor product surfaces. In this article we try to explain the relationship between the classic algebraic point of view and the practical geometrical application on NURBS.