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The immune system is able to protect the host from tumor onset, and immune deficiencies
are accompanied by an increased risk of cancer. Immunology is one of the fields in biology
where the role of computational and mathematical modeling and analysis were recognized the
earliest, beginning from 60s of the last century. We introduce the two most common methods
in simulating the competition among the immune system, cancers and tumor immunology
strategies:...
This article is devoted to the construction of a mathematical model describing the early
formation of atherosclerotic lesions. The early stage of atherosclerosis is an
inflammatory process that starts with the penetration of low density lipoproteins in the
intima and with their oxidation. This phenomenon is closely linked to the local blood flow
dynamics. Extending a previous work [5] that was mainly restricted to a
one-dimensional setting, we couple...
This article focuses on heat radiation intensity optimization on the surface of a shell metal mould. Such moulds are used in the automotive industry in the artificial leather production (the artificial leather is used, e.g., on car dashboards). The mould is heated by infrared heaters. After the required temperature is attained, the inner mould surface is sprinkled with special PVC powder. The powder melts and after cooling down it forms the artificial leather. A homogeneous temperature field of...
The paper is devoted to mathematical modelling and numerical computations of a
nonstationary
free boundary problem. The model is based on processes of molecular diffusion of
some
products of chemical decomposition of a solid organic substance concentrated in
bottom sediments.
It takes into account non-stationary multi-component and multi-stage chemical
decomposition of
organic substances and the processes of sorption desorption under aerobic and
anaerobic conditions.
Such a model allows one to...
A pneumatic tyre in rotating motion with a constant angular velocity is assimilated to a torus whose generating circle has a radius . The contact of the tyre with the ground is schematized as an ellipse with semi-major axis . When and (where is the velocity of the sound), we show that at the rapid time scale , the air motion within a torus periodically excited on its surface generates an acoustic wave . A study of this acoustic wave is conducted and shows that the mode associated to...
Solid tumors and hematological cancers contain small population of tumor cells that are
believed to play a critical role in the development and progression of the disease. These
cells, named Cancer Stem Cells (CSCs), have been found in leukemia, myeloma, breast,
prostate, pancreas, colon, brain and lung cancers. It is also thought that CSCs drive the
metastatic spread of cancer. The CSC compartment features a specific and phenotypically
defined cell...
Plant growth occurs due to cell proliferation in the meristem. We model the case of
apical meristem specific for branch growth and the case of basal meristem specific for
bulbous plants and grass. In the case of apical growth, our model allows us to describe
the variety of plant forms and lifetimes, endogenous rhythms and apical domination. In the
case of basal growth, the spatial structure, which corresponds to the appearance of
leaves, results...
We consider an ecosystem in which
spiders may be transported by the wind from vineyards into the
surrounding woods and vice versa. The model takes into account
this tranport phenomenon without building space explicitly into
the governing equations. The equilibria of the dynamical system
are analyzed together with their stability, showing that
bifurcations may occur. Then the effects of indiscriminated
spraying to keep pests under control is also investigated via
suitable simulations.
Two main approaches have been considered for modelling the dynamics of the SIS model on
complex metapopulations, i.e, networks of populations connected by migratory flows whose
configurations are described in terms of the connectivity distribution of nodes (patches)
and the conditional probabilities of connections among classes of nodes sharing the same
degree. In the first approach migration and transmission/recovery process alternate
sequentially,...
Tuberculosis (TB) is the leading cause of death among individuals infected with the
hepatitis B virus (HBV). The study of the joint dynamics of HBV and TB present formidable
mathematical challenges due to the fact that the models of transmission are quite
distinct. We formulate and analyze a deterministic mathematical model which incorporates
of the co-dynamics of hepatitis B and tuberculosis. Two sub-models, namely: HBV-only and
TB-only sub-models...
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