Computing linking numbers of a filtration.
The nonlocal Fisher equation has been proposed as a simple model exhibiting Turing instability and the interpretation refers to adaptive evolution. By analogy with other formalisms used in adaptive dynamics, it is expected that concentration phenomena (like convergence to a sum of Dirac masses) will happen in the limit of small mutations. In the present work we study this asymptotics by using a change of variables that leads to a constrained Hamilton-Jacobi equation. We prove the convergence analytically...
We introduce and study conditional differential equations, a kind of random differential equations. We give necessary and sufficient conditions for the existence of a solution of such an equation. We apply our main result to a Malthus type model.
Nel panorama della scienza contemporanea, la biologia molecolare ha recentemente assunto un ruolo di fondamentale importanza. Il bisognocrescente di conoscere intere sequenze genomiche e l’esigenza, ancora piùpressante, di analizzare e confrontare tali sequenze per poter dedurre funzionalità e discendenze comuni, ha reso necessaria l’integrazione delleusuali tecniche sperimentali, proprie della ricerca biologica, con le metodologie formali della matematica e dell’informatica. Queste motivazioni...
A common framework for analyzing the global convergence of several flows for principal component analysis is developed. It is shown that flows proposed by Brockett, Oja, Xu and others are all gradient flows and the global convergence of these flows to single equilibrium points is established. The signature of the Hessian at each critical point is determined.
National policies regarding the BCG vaccine for tuberculosis vary greatly throughout the international community and several countries are currently considering discontinuing universal vaccination. Detractors of BCG point to its uncertain effectiveness and its interference with the detection and treatment of latent tuberculosis infection (LTBI). In order to quantify the trade-off between vaccination and treatment of LTBI, a mathematical model was designed and calibrated to data from Brazil, Ghana,...