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Background: Community-acquired methicillin-resistant Staphylococcus
aureus (CA-MRSA), a novel strain of MRSA, has recently emerged and rapidly
spread in the community. Invasion into the hospital setting with replacement of the
hospital-acquired MRSA (HA-MRSA) has also been documented. Co-colonization with both
CA-MRSA and HA-MRSA would have important clinical implications given differences in
antimicrobial susceptibility profiles and the potential...
In this paper we explore a new model of field carcinogenesis, inspired by lung
cancer precursor lesions, which includes dynamics of a spatially distributed population of
pre-cancerous cells c(t, x), constantly supplied by an influx μ of mutated normal cells. Cell
proliferation is controlled by growth factor molecules bound to cells, b(t, x). Free growth
factor molecules g(t, x) are produced by precancerous cells and may diffuse before they become
bound to other cells. The purpose of modelling is...
In this paper the authors raise the issue of automatic discrimination of atherosclerotic plaques within an artery lumen based on numerical and statistical thresholding of Computerized Tomography Angiographic (CTA) images and their advanced dimensioning as a support for preoperative vessel assessment. For the study, a set of tomograms of the aorta, as well as the ilio-femoral and femoral arteries were examined. In each case a sequence of about 130-480 images of the artery cutoff planes were analyzed...
Ionizing radiation activates a large variety of intracellular mechanisms responsible for maintaining appropriate cell functionality or activation of apoptosis which eliminates damaged cells from the population. The mechanism of such induced cellular death is widely used in radiotherapy in order to eliminate cancer cells, although in some cases it is highly limited by increased cellular radio-resistance due to aberrations in molecular regulation mechanisms of malignant cells. Despite the positive...
The fully coupled description of blood flow and mass transport in
blood vessels requires extremely robust numerical methods. In order
to handle the heterogeneous coupling between blood flow and plasma filtration,
addressed by means of Navier-Stokes and Darcy's equations,
we need to develop a numerical scheme capable to deal with
extremely variable parameters, such as the blood viscosity and
Darcy's permeability of the arterial walls. In this paper, we describe a finite element method for...
The fully coupled description of blood flow and mass transport in
blood vessels requires extremely robust numerical methods. In order
to handle the heterogeneous coupling between blood flow and plasma filtration,
addressed by means of Navier-Stokes and Darcy's equations,
we need to develop a numerical scheme capable to deal with
extremely variable parameters, such as the blood viscosity and
Darcy's permeability of the arterial walls. In this paper, we describe a finite element method for...
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