How to improve efficiency of analysis of sequential data?
The aim of this paper is to give a general idea to state optimality conditions of control problems in the following form: , (1) where is a set of admissible controls and is the solution of the following equation: ; . (2). The results are nonlocal and new.
HIV infection is multi-faceted and a multi-step process. The virus-induced pathogenic mechanisms are manifold and mediated through a range of positive and negative feedback regulations of immune and physiological processes engaged in virus-host interactions. The fundamental questions towards understanding the pathogenesis of HIV infection are now shifting to ‘dynamic’ categories: (i) why is the HIV-immune response equilibrium finally disrupted? (ii)...
The paper proposes a design procedure for the creation of a robust and effective hybrid algorithm, tailored to and capable of carrying out a given design optimisation task. In the course of algorithm creation, a small set of simple optimisation methods is chosen, out of which those performing best will constitute the hybrid algorithm. The simplicity of the method allows implementing ad-hoc modifications if unexpected adverse features of the optimisation problem are found. It is postulated to model...
We consider stabilizing a discrete-time LTI (linear time-invariant) system via state feedback where both the quantized state and control input signals are involved. The system under consideration is stabilizable and stabilizing state feedback has been designed without considering quantization, but the system's stability is not guaranteed due to the quantization effect. For this reason, we propose a hybrid quantized state feedback strategy asymptotically stabilizing the system, where the values of...
We show that solutions to some Hamilton-Jacobi Equations associated to the problem of optimal control of stochastic semilinear equations enjoy the hypercontractivity property.
Haar's Lemma (1918) deals with the algebraic characterization of the inclusion of polyhedral sets. This Lemma has been involved many times in automatic control of linear dynamical systems via positive invariance of polyhedrons. More recently, it has been used to characterize stochastic comparison w.r.t. linear/integral ordering of Markov (reward) chains. In this paper we develop a state space oriented approach to the control of Discrete Event Systems (DES) based on the remark that most of control...
The aim of this paper is numerical estimation of pharmacokinetic parameters of the ligands of the macrophage mannose receptor, without knowing it a priori the values of these parameters. However, it first requires a model identifiability analysis, which is done by applying an algorithm implemented in a symbolic computation language. It is shown that this step can lead to a direct numerical estimation algorithm. In this way, a first estimate is computed from noisy simulated observations without it...
We study the identification of the nonlinearities A,(→)b and c appearing in the quasilinear parabolic equation y_t − div(A(y)∇y + (→)b(y)) + c(y) = u inΩ × (0,T), assuming that the solution of an associated boundary value problem is known at the terminal time, y(x,T), over a (probably small) subset of Ω, for each source term u. Our work can be divided into two parts. Firstly, the uniqueness of A,(→)b and c is proved under appropriate assumptions. Secondly, we consider a finite-dimensional optimization...