Let $K$ be a field of odd characteristic $p$, let $f\left(x\right)$ be an irreducible separable polynomial of degree $n\ge 5$ with big Galois group (the symmetric group or the alternating group). Let $C$ be the hyperelliptic curve $y^2=f\left(x\right)$ and $J\left(C\right)$ its jacobian. We prove that $J\left(C\right)$ does not have nontrivial endomorphisms over an algebraic closure of $K$ if either $n\ge 7$ or $p\ne 3$.