Page 1

Displaying 1 – 10 of 10

Showing per page

Biochemical network of drug-induced enzyme production: Parameter estimation based on the periodic dosing response measurement

Volodymyr Lynnyk, Štěpán Papáček, Branislav Rehák (2021)

Kybernetika

The well-known bottleneck of systems pharmacology, i. e., systems biology applied to pharmacology, refers to the model parameters determination from experimentally measured datasets. This paper represents the development of our earlier studies devoted to inverse (ill-posed) problems of model parameters identification. The key feature of this research is the introduction of control (or periodic forcing by an input signal being a drug intake) of the nonlinear model of drug-induced enzyme production...

Boundary layer phenomenon for three -point boundary value problem for the nonlinear singularly perturbed systems

Robert Vrabel (2011)

Kybernetika

This paper deals with the three-point boundary value problem for the nonlinear singularly perturbed second-order systems. Especially, we focus on an analysis of the solutions in the right endpoint of considered interval from an appearance of the boundary layer point of view. We use the method of lower and upper solutions combined with analysis of the integral equation associated with the class of nonlinear systems considered here.

Boundary value problem for an infinite system of second order differential equations in p spaces

Ishfaq Ahmad Malik, Tanweer Jalal (2020)

Mathematica Bohemica

The concept of measures of noncompactness is applied to prove the existence of a solution for a boundary value problem for an infinite system of second order differential equations in p space. We change the boundary value problem into an equivalent system of infinite integral equations and result is obtained by using Darbo’s type fixed point theorem. The result is illustrated with help of an example.

Currently displaying 1 – 10 of 10

Page 1