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Modeling the Cancer Stem Cell Hypothesis

C. Calmelet, A. Prokop, J. Mensah, L. J. McCawley, P. S. Crooke (2010)

Mathematical Modelling of Natural Phenomena

Solid tumors and hematological cancers contain small population of tumor cells that are believed to play a critical role in the development and progression of the disease. These cells, named Cancer Stem Cells (CSCs), have been found in leukemia, myeloma, breast, prostate, pancreas, colon, brain and lung cancers. It is also thought that CSCs drive the metastatic spread of cancer. The CSC compartment features a specific and phenotypically defined cell...

Normal forms of analytic perturbations of quasihomogeneous vector fields: Rigidity, invariant analytic sets and exponentially small approximation

Eric Lombardi, Laurent Stolovitch (2010)

Annales scientifiques de l'École Normale Supérieure

In this article, we study germs of holomorphic vector fields which are “higher order” perturbations of a quasihomogeneous vector field in a neighborhood of the origin of ℂ n , fixed point of the vector fields. We define a “Diophantine condition” on the quasihomogeneous initial part S which ensures that if such a perturbation of S is formally conjugate to S then it is also holomorphically conjugate to it. We study the normal form problem relatively to S . We give a condition on S that ensures that there...

Numerical schemes for multivalued backward stochastic differential systems

Lucian Maticiuc, Eduard Rotenstein (2012)

Open Mathematics

We define approximation schemes for generalized backward stochastic differential systems, considered in the Markovian framework. More precisely, we propose a mixed approximation scheme for the following backward stochastic variational inequality: d Y t + F ( t , X t , Y t , Z t ) d t ∈ ∂ φ ( Y t ) d t + Z t d W t , where ∂φ is the subdifferential operator of a convex lower semicontinuous function φ and (X t)t∈[0;T] is the unique solution of a forward stochastic differential equation. We use an Euler type scheme for the system of decoupled forward-backward variational...

On a stochastic SIR model

Elisabetta Tornatore, Stefania Maria Buccellato (2007)

Applicationes Mathematicae

We consider a stochastic SIR system and we prove the existence, uniqueness and positivity of solution. Moreover the existence of an invariant measure under a suitable condition on the coefficients is studied.

On small solutions of second order differential equations with random coefficients

László Hatvani, László Stachó (1998)

Archivum Mathematicum

We consider the equation x ' ' + a 2 ( t ) x = 0 , a ( t ) : = a k if t k - 1 ≤ t < t k , for k = 1 , 2 , ... , where { a k } is a given increasing sequence of positive numbers, and { t k } is chosen at random so that { t k - t k - 1 } are totally independent random variables uniformly distributed on interval [ 0 , 1 ] . We determine the probability of the event that all solutions of the equation tend to zero as t → ∞ .

Path formulation for multiparameter 𝔻 3 -equivariant bifurcation problems

Jacques-Élie Furter, Angela Maria Sitta (2010)

Annales de l’institut Fourier

We implement a singularity theory approach, the path formulation, to classify 𝔻 3 -equivariant bifurcation problems of corank 2, with one or two distinguished parameters, and their perturbations. The bifurcation diagrams are identified with sections over paths in the parameter space of a 𝔻 3 -miniversal unfolding F 0 of their cores. Equivalence between paths is given by diffeomorphisms liftable over the projection from the zero-set of F 0 onto its unfolding parameter space. We apply our results to degenerate...

Peano type theorem for random fuzzy initial value problem

Marek T. Malinowski (2011)

Discussiones Mathematicae, Differential Inclusions, Control and Optimization

In this paper we consider the random fuzzy differential equations and show their application by an example. Under suitable conditions the Peano type theorem on existence of solutions is proved. For our purposes, a notion of ε-solution is exploited.

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