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Influence of time delays on the Hahnfeldt et al. angiogenesis model dynamics

Marek Bodnar, Urszula Foryś (2009)

Applicationes Mathematicae

We study the influence of time delays on the dynamics of the general Hahnfeldt et al. model of an angiogenesis process. We analyse the dynamics of the system for different values of the parameter α which reflects the strength of stimulation of the vessel formation process. Time delays are introduced in three subprocesses: tumour growth, stimulation and inhibition of vessel formation (represented by endothelial cell dynamics). We focus on possible destabilisation of the positive steady state due...

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