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New Computational Tools for Modeling Chronic Myelogenous Leukemia

M. M. Peet, P. S. Kim, S.-I. Niculescu, D. Levy (2009)

Mathematical Modelling of Natural Phenomena

In this paper, we consider a system of nonlinear delay-differential equations (DDEs) which models the dynamics of the interaction between chronic myelogenous leukemia (CML), imatinib, and the anti-leukemia immune response. Because of the chaotic nature of the dynamics and the sparse nature of experimental data, we look for ways to use computation to analyze the model without employing direct numerical simulation. In particular, we develop several tools using Lyapunov-Krasovskii analysis that allow...

New results on global exponential stability of almost periodic solutions for a delayed Nicholson blowflies model

Bingwen Liu (2015)

Annales Polonici Mathematici

This paper is concerned with a class of Nicholson's blowflies models with multiple time-varying delays, which is defined on the nonnegative function space. Under appropriate conditions, we establish some criteria to ensure that all solutions of this model converge globally exponentially to a positive almost periodic solution. Moreover, we give an example with numerical simulations to illustrate our main results.

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