Identifying generalized Fitzhugh-Nagumo equation from a numerical solution of Hodgkin-Huxley model.
Despite recent advances, treatment of patients with aggressive Non-Hodgkin's lymphoma (NHL2) has yet to be optimally designed. Notwithstanding the contribution of molecular treatments, intensification of chemotherapeutic regimens may still be beneficial. Hoping to aid in the design of intensified chemotherapy, we put forward a mathematical and computational model that analyses the effect of Doxorubicin on NHL over a wide range of patho-physiological conditions. The model represents tumour growth...
We consider the topological category of various subsets of the set of expanding maps from a manifold to itself, and show in particular that a generic expanding map of the circle has no absolutely continuous invariant probability measure. This is in contrast with the situation for or expanding maps, for which it is known that there is always a unique absolutely continuous invariant probability measure.
An overview of multivariate modelling based on logistic and exponential smooth transition models with transition variable generated by aggregation operators and orders of auto and exogenous regression selected by information criterion separately for each regime is given. Model specification procedure is demonstrated on trivariate exchange rates time series. The application results show satisfactory improvement in fit when particular aggregation operators are used. Source code in the form of Mathematica...
This paper is mainly concerned with a class of optimal control problems of systems governed by the nonlinear dynamic systems on time scales. Introducing the reasonable weak solution of nonlinear dynamic systems, the existence of the weak solution for the nonlinear dynamic systems on time scales and its properties are presented. Discussing L1-strong-weak lower semicontinuity of integral functional, we give sufficient conditions for the existence of optimal controls. Using integration by parts formula...
This paper is mainly concerned with a class of optimal control problems of systems governed by the nonlinear dynamic systems on time scales. Introducing the reasonable weak solution of nonlinear dynamic systems, the existence of the weak solution for the nonlinear dynamic systems on time scales and its properties are presented. Discussing L1-strong-weak lower semicontinuity of integral functional, we give sufficient conditions for the existence of optimal controls. Using integration by parts formula...
In long-time numerical integration of Hamiltonian systems, and especially in molecular dynamics simulation, it is important that the energy is well conserved. For symplectic integrators applied with sufficiently small step size, this is guaranteed by the existence of a modified Hamiltonian that is exactly conserved up to exponentially small terms. This article is concerned with the simplified Takahashi-Imada method, which is a modification of the Störmer-Verlet method that is as easy to implement...
This paper presents two algorithms for one-parameter local bifurcations of equilibrium points of dynamical systems. The algorithms are implemented in the computer algebra system Maple 13 © and designed as a package. Some examples are reported to demonstrate the package’s facilities.* This paper is partially supported by the Bulgarian Science Fund under grant Nr. DO 02–359/2008.