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Stippling the Skin: Generation of Anatomical Periodicity by Reaction-Diffusion Mechanisms

D. J. Headon, K. J. Painter (2009)

Mathematical Modelling of Natural Phenomena

During vertebrate development cells acquire different fates depending largely on their location in the embryo. The definition of a cell's developmental fate relies on extensive intercellular communication that produces positional information and ultimately generates an appropriately proportioned anatomy. Here we place reaction-diffusion mechanisms in the context of general concepts regarding the generation of positional information during development and then focus on these mechanisms as parsimonious...

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