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Asymptotic behaviour of a discrete dynamical system generated by a simple evolutionary process

Iwona Karcz-Dulęba (2004)

International Journal of Applied Mathematics and Computer Science

A simple model of phenotypic evolution is introduced and analysed in a space of population states. The expected values of the population states generate a discrete dynamical system. The asymptotic behaviour of the system is studied with the use of classical tools of dynamical systems. The number, location and stability of fixed points of the system depend on parameters of a fitness function and the parameters of the evolutionary process itself. The influence of evolutionary process parameters on...

Asymptotic sampling formulae for 𝛬 -coalescents

Julien Berestycki, Nathanaël Berestycki, Vlada Limic (2014)

Annales de l'I.H.P. Probabilités et statistiques

We present a robust method which translates information on the speed of coming down from infinity of a genealogical tree into sampling formulae for the underlying population. We apply these results to population dynamics where the genealogy is given by a 𝛬 -coalescent. This allows us to derive an exact formula for the asymptotic behavior of the site and allele frequency spectrum and the number of segregating sites, as the sample size tends to . Some of our results hold in the case of a general 𝛬 -coalescent...

Bacteriophage Infection Dynamics: Multiple Host Binding Sites

H. L. Smith, R. T. Trevino (2009)

Mathematical Modelling of Natural Phenomena

We construct a stochastic model of bacteriophage parasitism of a host bacteria that accounts for demographic stochasticity of host and parasite and allows for multiple bacteriophage adsorption to host. We analyze the associated deterministic model, identifying the basic reproductive number for phage proliferation, showing that host and phage persist when it exceeds unity, and establishing that the distribution of adsorbed phage on a host is binomial with slowly evolving mean. Not surprisingly,...

Cell Modelling of Hematopoiesis

N. Bessonov, L. Pujo-Menjouet, V. Volpert (2010)

Mathematical Modelling of Natural Phenomena

In this work, we introduce a new software created to study hematopoiesis at the cell population level with the individually based approach. It can be used as an interface between theoretical works on population dynamics and experimental observations. We show that this software can be useful to study some features of normal hematopoiesis as well as some blood diseases such as myelogenous leukemia. It is also possible to simulate cell communication and the formation of cell colonies in the bone marrow. ...

Comparison of Perron and Floquet Eigenvalues in Age Structured Cell Division Cycle Models

J. Clairambault, S. Gaubert, Th. Lepoutre (2009)

Mathematical Modelling of Natural Phenomena

We study the growth rate of a cell population that follows an age-structured PDE with time-periodic coefficients. Our motivation comes from the comparison between experimental tumor growth curves in mice endowed with intact or disrupted circadian clocks, known to exert their influence on the cell division cycle. We compare the growth rate of the model controlled by a time-periodic control on its coefficients with the growth rate of stationary models of the same nature, but with averaged coefficients....

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