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A Computational Framework to Assess the Efficacy of Cytotoxic Molecules and Vascular Disrupting Agents against Solid Tumours

M. Pons-Salort, B. van der Sanden, A. Juhem, A. Popov, A. Stéphanou (2012)

Mathematical Modelling of Natural Phenomena

A computational framework for testing the effects of cytotoxic molecules, specific to a given phase of the cell cycle, and vascular disrupting agents (VDAs) is presented. The model is based on a cellular automaton to describe tumour cell states transitions from proliferation to death. It is coupled with a model describing the tumour vasculature and its adaptation to the blood rheological constraints when alterations are induced by VDAs treatment....

A Computer Algebra Application to Determination of Lie Symmetries of Partial Differential Equations

Pulov, Vladimir, Chacarov, Edy, Uzunov, Ivan (2007)

Serdica Journal of Computing

The paper has been presented at the 12th International Conference on Applications of Computer Algebra, Varna, Bulgaria, June, 2006A MATHEMATICA package for finding Lie symmetries of partial differential equations is presented. The package is designed to create and solve the associated determining system of equations, the full set of solutions of which generates the widest permissible local Lie group of point symmetry transformations. Examples illustrating the functionality of the package's tools...

A conjecture on multivariate polynomial interpolation.

Jesús Miguel Carnicer, Mariano Gasca (2001)

RACSAM

La generalización de las fórmulas de interpolación de Lagrange y Newton a varias variables es uno de los temas habituales de estudio en interpolación polinómica. Dos clases de configuraciones geométricas particularmente interesantes en el plano fueron obtenidas por Chung y Yao en 1978 para la fórmula de Lagrange y por Gasca y Maeztu en 1982 para la de Newton. Estos últimos autores conjeturaron que toda configuración de la primera clase es de la segunda, y probaron que el recíproco no es cierto....

A conjugate gradient method with quasi-Newton approximation

Jonas Koko (2000)

Applicationes Mathematicae

The conjugate gradient method of Liu and Storey is an efficient minimization algorithm which uses second derivatives information, without saving matrices, by finite difference approximation. It is shown that the finite difference scheme can be removed by using a quasi-Newton approximation for computing a search direction, without loss of convergence. A conjugate gradient method based on BFGS approximation is proposed and compared with existing methods of the same class.

A conservative spectral element method for the approximation of compressible fluid flow

Kelly Black (1999)

Kybernetika

A method to approximate the Euler equations is presented. The method is a multi-domain approximation, and a variational form of the Euler equations is found by making use of the divergence theorem. The method is similar to that of the Discontinuous-Galerkin method of Cockburn and Shu, but the implementation is constructed through a spectral, multi-domain approach. The method is introduced and is shown to be a conservative scheme. A numerical example is given for the expanding flow around a point...

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