In this paper we develop fundamental tools and methods to study meromorphic functions in an equivariant setup. As our main result we construct quotients of Rosenlicht-type for Stein spaces acted upon holomorphically by complex-reductive Lie groups and their algebraic subgroups. In particular, we show that in this setup invariant meromorphic functions separate orbits in general position. Applications to almost homogeneous spaces and principal orbit types are given. Furthermore, we use the main result...