Let 1 ≤ p < ∞, $={\left(Xₙ\right)}_{n\in \mathbb{N}}$ be a sequence of Banach spaces and $l_p\left(\right)$ the coresponding vector valued sequence space. Let $={\left(Xₙ\right)}_{n\in \mathbb{N}}$, $={\left(Yₙ\right)}_{n\in \mathbb{N}}$ be two sequences of Banach spaces, $={\left(Vₙ\right)}_{n\in \mathbb{N}}$, Vₙ: Xₙ → Yₙ, a sequence of bounded linear operators and 1 ≤ p,q < ∞. We define the multiplication operator $M_{}:l_p\left(\right)\to l_q\left(\right)$ by $M_{}\left({\left(xₙ\right)}_{n\in \mathbb{N}}\right):={\left(Vₙ\left(xₙ\right)\right)}_{n\in \mathbb{N}}$. We give necessary and sufficient conditions for $M_{}$ to be 2-summing when (p,q) is one of the couples (1,2), (2,1), (2,2), (1,1), (p,1), (p,2), (2,p), (1,p), (p,q); in the last case 1 < p < 2, 1 < q < ∞.