On a class of distribution-free tests for growth curves analyses
On an asymptotic optimality property of play-the-winner and vector-at-a-time sampling.
Simon and Weiss (1975) consider the formulation of the clinical trial as a selection procedure (Bechhofer, Kiefer and Sobel, 1968). The object of the trial is to choose the better treatment with probability ≥ P*, where P* is assigned, when the difference in success probabilities is ≥ Δ*, Δ* also being assigned. They consider a family of single step allocation methods for the reduction of the number of patients given the poorer treatment. Using numerical results, Simon and Weiss conclude that if...
On distribution of waiting time for the first failure followed by a limited length success run
Many doctors believe that a patient will survive a heart attack unless a succeeding attack occurs in a week. Treating heart attacks as failures in Bernoulli trials we reduce the lifetime after a heart attack to the waiting time for the first failure followed by a success run shorter than a given k. In order to test the "true" critical period of the lifetime we need its distribution. The probability mass function and cumulative distribution function of the waiting time are expressed in explicit and...
On equivalence and bioequivalence testing.
Equivalence testing is the natural approach to many statistical problems. First, its main application, bioequivalence testing, is reviewed. The basic concepts of bioequivalence testing (2×2 crossover designs, TOST, interval inclusion principle, etc.) and its problems (TOST biased character, the carryover problem, etc.) are considered. Next, equivalence testing is discussed more generally. Some applications and methods are reviewed and the relation of equivalence testing and distance-based inference...
On iterates of strong Feller operators on ordered phase spaces
Let (X,d) be a metric space where all closed balls are compact, with a fixed σ-finite Borel measure μ. Assume further that X is endowed with a linear order ⪯. Given a Markov (regular) operator P: L¹(μ) → L¹(μ) we discuss the asymptotic behaviour of the iterates Pⁿ. The paper deals with operators P which are Feller and such that the μ-absolutely continuous parts of the transition probabilities are continuous with respect to x. Under some concentration assumptions on the asymptotic transition probabilities...
On small sample inference for common mean in heteroscedastic one-way model
In this paper we consider and compare several approximate methods for making small-sample statistical inference on the common mean in the heteroscedastic one-way random effects model. The topic of the paper was motivated by the problem of interlaboratory comparisons and is also known as the (traditional) common mean problem. It is also closely related to the problem of multicenter clinical trials and meta-analysis. Based on our simulation study we suggest to use the approach proposed by Kenward...
On the similarity of sets
On the translated exponential model with censoring.
Optimization in HIV screening problems.